Yes, monkey balls(brains) or the more common name Osage Orange is native to the Osage River valley...
Osage Orange has been spread through out North America because of there use as a living fence.
Live2Bowhunt said:
The fact that they are so thorny is why they made such a good living fence. Once barb wire was invented, there wasn't as much a need for them though. Today, they are scattered throughout Pennsylvania, most along stream bottoms. Their fruits can be carried by the river for miles.
From Wikipedia: "The Osage-orange is commonly used as a tree row windbreak in prairie states, which gives it one of its colloquial names, "hedge apple". It was one of the primary trees used in President Franklin Delano Roosevelt's "Great Plains Shelterbelt" WPA project, which was launched in 1934 as an ambitious plan to modify weather and prevent soil erosion in the Great Plains states, and by 1942 resulted in the planting of 30,233 shelterbelts containing 220 million trees that stretched for 18,600 miles (29,900 km).[7] The sharp-thorned trees were also planted as cattle-deterring hedges before the introduction of barbed wire and afterward became an important source of fence posts.
The heavy, close-grained yellow-orange wood is very dense and is prized for tool handles, treenails, fence posts, electrical insulators, and other applications requiring a strong dimensionally stable wood that withstands rot. Straight-grained osage timber (most is knotty and twisted) makes very good bows. In Arkansas, in the early 19th century, a good Osage bow was worth a horse and a blanket.[3] Additionally, a yellow-orange dye can be extracted from the wood, which can be used as a substitute for fustic and aniline dyes. When dried, the wood also makes excellent fire wood that burns long and hot.[8]
Today, the fruit is sometimes used to deter spiders, cockroaches, boxelder bugs, crickets, fleas, and other arthropods. An article posted by the Burke Museum in Washington State claims that this usage, in the case of spiders, has no evidence to support it.[9]"