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I,ve asked this on a few other forums but wanted to as all you fellas also. What caliber would work for deer and also coyote without making a mess of them. I just started reloading so maybe a reduced load for yotes and a regular load for deer at say 250yds. Is there such a thing?
 

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243, 2506 and 270 of the std calibers I feel are the best over the last 25 years I have used these in just such a application with the 2506 and the 270 tied for first I also used 6mm rem, ,708 among others in the last 3 years I have taken 11 coyotes and 8 deer with the 270 in 2 different rifles and I am working on a new load for the 2506 using a 115 grain Nosler Pt
 

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I use my 22-250 with 45gr Barnes TSX, drops deer like a hand grende went off inside them and pokes a hole thru smaller animals. a 260 rem would be a good choice also.
 

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Anything .243 to .270 will work. Don't mess with reduced loads for coyotes. Use your deer load and it will punch right through them without opening much. I just sold a .260 in the classifieds I've been using for this. Been thinking about picking up a .357 Marlin to try next year with cast bullets.
 

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just got a 25 06 amazed at the performance.
 

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I doubt you could really go much bigger than a 243 without making a total mess of coyotes. I'd not be afraid to get a 22-250 or 223 with the right twist for both, though to err on the side of caution, I'd say the 243 is the best choice if you plan on killing deer and have any intentions of being "fur friendly".

A 243 loaded with either the Barnes 80 grain TTSX or 85 TSX is bad mojo on critters.
 
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