Referring to Lyman 49th edition; I used H322 powder, R-P brass, Cast Performance Bullets; 405gr WLN-GC/0.459 diameter & Winchester lg rifle magnum primers(I adjusted each load down by 1.5gr.) I started with the lightest load and worked up to the max. I found that my particular rifle, which has a ported 18 1/2 in barrel, LOVED 47gr at an OAL of 2.546.
I put an XS sight systems scout mount on it along with their ghost ring rear & front sight; mounted a Leupold FX-II IER scope on her. Alas; saw no bear!!
I also installed the Wild West lg loop lever, Happy Trigger, and their Bear proof extracter & polished up all of the tool marks on the actions.
Just my input; hope it helps. THIS IS THE LOAD THAT I USE & I ASSUME NO RESPONSIBILITY FOR ANY OTHERS WHO ATTEMPT USING THIS LOAD.