I usually get flamed for my comments on the quarter bore. but I am a big boy and I can take it. I have owned one 25-06, two 257 Wbys., one 250 Savage, and two 257 Roberts rifles. I still have one of the Robert's. It was a rifle my uncle left me, so I would never sell it.
Personally I do not like the cartridges. IMO they are too big for the little stuff, and too little for the big stuff. Way too much for a varmint rig-just not needed-pure overkill. And for larger game such as deer I have witnessed and suffered from poor performance from the quarter bores. So basically I do not have any use for them.
Also the bullet selection for the quarter bores is relatively poor when considered against the other calibers.
I consider the 6.5 mm as the minimum for deer. And I really like the BC's of the 6.5 mm bullets, as well as the 7 mm bullets.
I know a lot of guys like the quarter bores. And I say what the heck. If you want one then buy one. But I do not think they are a multi-purpose cartridge. If I really only could have one rifle, and it needed to be a multi-purpose cartridge then I would either go with a 260 Remington, the 6.5X55, or the new Hornady 6.5 Creedmore. But thankfully I can have more than one rifle. Tom.