You will need your up to date passport. I would also take along one other photo ID. A credit card or two is also a good idea.
As to vaccinations, a good place to start would be your family doctor, or if you have a branch of Occupational Health Services close to where you live, they do this sort of thing all the time. You should start on vaccinations about six to eight months before you plan to leave for Africa if I remember correctly, since one of the vaccinations required a booster. I think we updated our tetanus and polio, got shots for hepatitus, cholera, and a few other things.
Check with your outfitter to see if malaria will be a problem in the area in which you will be hunting. There are several malaria prophylactics available. If so, your doctor will prescribe a preventive to take with you. We took larium. It does give some people hallucinogenic dreams, and I kinda enjoyed them.
I would also suggest that you check with your health insurance provider and see how extensive your coverage is when in Africa. Hopefully you will not need it, but we also took out a trip insurance policy to cover medical evacuation and/or hospitalization. This could be important if you are hunting dangerous game for sure.
My W 1 FE unit and I have been to Africa three times, so if you have any other questions, feel free to drop me a pm.