With a round ball, keep in mind that with the same powder charge, it is moving a lot faster. Air resistance really doesn't play a factor until about the 60 to 75 yd point. Considering that most deer in PA are hit at about 30 yards, you are good to go. However, a 45 round ball is no long range item, but neither is a 54 round ball. If you were to go to conicals, remember that buffalo hunters using cross sticks were capable of great accuracy and killing power to 400 yds with a 45 caliber bullet. Read about the original Creedmore matched in which 45 caliber muzzle loaders were capable of great accuracy to some pretty long distances. They were frequently shot to 1,000 yds, but the target was almost as big as a 4 x 8 sheet of plywood at that distance. Some shooters with modern muzzle loader barrels, fast twist and false muzzles are shooting much smaller 1,000 yd groups.