We will need a lot more information first. Are you familiar with pistols, what is your budget, will this be a dual purpose gun, Range and carry. Are you looking at revolvers or semi. Your question as ask is like saying you need transportation. That could be anything from a bicycle to a one ton truck.
No one's going to be able to suggest the perfect gun for you. Give us more information and we can give you a handful to go check out. Once you have them all in your hand you will know which one is right for you.
Semi vs Revolver
All the above come into play and more.
Don't Tread On Me is what it says and I'll take that to my grave.