Years ago I would have said Centre Co., but since I live here now that's off the table(although I'd still like to have 100 acres). Right now I would go somewhere in the northern tier. Somewhere between ANF and Wellsboro area.
The mtns of Fayette county. Lots of public lands to hunt etc but also for me very close to the Yough river, fishing and kayaking, and all the other close white water. Also good mtn biking. And I would settle for 20 acres