I have used the 185gr and 210 gr hunting VLD in my 300 RUM Sendero with great results. So far have taken 2 elk (one at 250 yards and the other at under 100, both pumped full of adrenaline) and a deer at 450 yards, along with a bunch of steel. The bergers do come apart like a grenade, but as long as you dont put them through the shoulder meat damage is minimal.
I use the 52 gr Varmint Match in my 22-250 with great results on P-dogs and coyotes. Have taken p-dogs out to 400, and they are great on yote pelts.
I would love to build a 6mm or 6.5mm like the one you describe, as I think paired with the Bergers would make a great long range yote or deer gun.
Or a 338 Edge....which I believe you have.