I travel alot with a gunbox. For starters,get a good box. I've seen cheap plastic boxes with holes punched through, hinges broken,and once saw one come off conveyor in Denver that was laid wide open.My Cabelas box has been on 21 trips,still like new. To your question,gunboxes are opened in the airport for the inspection by TSA,not because they contain guns, but because most are metal and don't X-ray well. TSA are not interested in your guns; they are looking for traces of explosives.Since you must open and close case for their inspection, TSA generic locks would not be needed. Note that in Canada,flying out Toronto or any Canadian airport, you must install trigger locks or lock cable in action,and ammo must be in shell case and packed in bag other than gunbox. Air Canada also shakes you down for 50 buck surcharge per box, each way,when flying guns. Can put 2 rifles in one box though.